Antonio S. Torralba
Universidad Complutense  

Chemistry

BBM1

Biophysics

 

FUNDER - Main Page


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Theoretical Background

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MAIN INDEX


1. Theoretical background

1.1. Signals

1.2. Systems

1.3. Susceptibilities

1.4. Neville's algorithm for polynomial extrapolation

1.5. Savitzky-Golay filters

2. FUNDER Documentation

2.1. Files

2.2. C++ classes

2.3. User-defined systems

3. Fructose catabolism - An example

3.1. System

3.2. Components

3.3. Rate equations

3.4. Parameters

3.5. Differential equations

4. Download and Compilation


WHAT IS THIS?


FUNDER is an application that illustrates the calculation of the susceptibilities of non-linear biochemical systems. As an example, it implements the dynamics of a part of fructose catabolism in terms of the differential equations of a model. It uses several C++ classes that are freely available as a library. For a description and compilation instructions, visit the documentation and download pages.


MOTIVATION


The response of a biochemical system can be formally represented as a functional transformation of the systemic inputs. In many instances, the functional must be expanded in a functional Taylor series, because an explicit form is not known. In order to do so, the susceptibilities of the system (or its functional derivatives) must be computed.


If you feel uncomfortable with functional derivatives, take a look at the theoretical pages.



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Last modified:
Monday, 04-Mar-2013 11:58:25 CET

© 2013 Antonio Sánchez Torralba